Researcher | Universidade do Porto | Portugal
Dr. C. M. Botelho, a senior researcher at the Universidade do Porto, Portugal, is a highly accomplished scientist whose work spans natural products chemistry, bioactive compounds, sustainable biomaterials, cosmetic formulation science, and microfluidic technologies. With advanced academic training in pharmaceutical sciences and bioactive natural products, Dr. Botelho has built a distinguished career centered on the chemical characterization, extraction, and application of plant-derived antioxidants, anti-inflammatory agents, and nutraceutical components. Over the years, Dr. Botelho has authored 70 peer-reviewed scientific publications, which have collectively accumulated over 2,061 citations and contributed to an impressive h-index of 25, demonstrating significant international influence and sustained scientific productivity. Her recent works include cutting-edge studies on microfluidic flow-focusing for cubosome formation, phenolic profiling of medicinal plants, sustainable recovery of olive-oil by-products, and the development of cosmetic creams enriched with grape stem extracts, highlighting her leadership in combining sustainability, biotechnology, and human health research. Additional notable contributions include investigations into anti-inflammatory phytochemicals, bioactive potential of grape stem blends for skin regeneration, and microwave-assisted extraction of raspberry pomace, advancing both food science and dermatological innovation. Dr. Botelho has collaborated with more than 240 co-authors from multidisciplinary fields, reflecting her strong international research network and ability to drive collaborative scientific advancements. Her scholarship not only contributes to greener industrial practices but also supports the development of innovative cosmetic, pharmaceutical, and nutraceutical products with societal and commercial impact. In addition to research excellence, Dr. Botelho actively contributes to the scientific community through peer-review service and involvement with international journals in natural products and pharmaceutical sciences. Her continued work positions her as a key contributor to sustainable bioproduct development and the future of functional plant-based innovations.
Featured Publications
1. Silva-Fernandes, A., Costa, M. D. C., Duarte-Silva, S., Oliveira, P., … Botelho, C. M. (2010). Motor uncoordination and neuropathology in a transgenic mouse model of Machado–Joseph disease lacking intranuclear inclusions and ataxin-3 cleavage products. Neurobiology of Disease.
2. Botelho, C. M., Brooks, R. A., Spence, G., McFarlane, I., Lopes, M. A., Best, S. M., … (2006). Differentiation of mononuclear precursors into osteoclasts on the surface of Si‐substituted hydroxyapatite. Journal of Biomedical Materials Research Part A.
3. Oliveira, C., Coelho, C., Teixeira, J. A., Ferreira-Santos, P., & Botelho, C. M. (2022). Nanocarriers as active ingredients enhancers in the cosmetic industry: The European and North America regulation challenges. Molecules.
4. Fernandes, M., Lopes, I., Magalhães, L., Sárria, M. P., Machado, R., Sousa, J. C., … (2021). Novel concept of exosome-like liposomes for the treatment of Alzheimer’s disease. Journal of Controlled Release.
5. Oliveira, C., Sousa, D., Teixeira, J. A., Ferreira-Santos, P., & Botelho, C. M. (2023). Polymeric biomaterials for wound healing. Frontiers in Bioengineering and Biotechnology.